Atrial Natriuretic Peptide Receptor 1

Preferred Label : Atrial Natriuretic Peptide Receptor 1;

NCIt synonyms : Guanylate Cyclase 2A; ANP-A; EC 4.6.1.2; NPR-A; Natriuretic Peptide Receptor A; GC-A; Natriuretic Peptide A Type Receptor; Atrionatriuretic Peptide Receptor A; Natriuretic Peptide Receptor A/Guanylate Cyclase A; Guanylate Cyclase A; Atrionatriuretic Peptide Receptor, Type A; ANPR-A; Atrial Natriuretic Peptide Receptor Type A; Atrial Natriuretic Peptide Receptor, Type A;

NCIt definition : Atrial natriuretic peptide receptor 1 (1061 aa, 119 kDa) is encoded by the human NPR1 gene. This protein plays a role in both guanylate cyclase activity and natriuretic peptide binding.;

Details

Origin ID

C112515;

UMLS CUI

C1529723;

Automatic exact mappings (from CISMeF team)
- Giant cell arteritis [ICD-11 Subcategory]
- Guanylate cyclase (substance) [SNOMED CT concept]
- Natriuretic peptide receptor a/guanylate cyclase a [OMIM gene]
- guanylate cyclase [SNOMED Notion]
- guanylate cyclase [MeSH concept]
- guanylate cyclase [MeSH Descriptor]
- natriuretic peptide receptor 1 [HGNC gene]
OMIM relation
- Natriuretic peptide receptor a/guanylate cyclase a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- NPR1 protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Lyase Gene [NCIt concept]
- NPR1 Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Guanylate Cyclase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Purine Metabolism Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Blood Circulation [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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