guanylate cyclase

Preferred Label : guanylate cyclase;

MeSH definition : An enzyme that catalyzes the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. It also acts on ITP and dGTP. (From Enzyme Nomenclature, 1992) EC 4.6.1.2.;

MeSH synonym : guanyl cyclase; inosinate cyclase; cyclase, inosinate; cyclase, guanylyl; deoxyguanylate cyclase; cyclase, deoxyguanylate; guanylyl cyclase; cyclase, guanylate; cyclase, guanyl;

MeSH CAS label : GTP pyrophosphate-lyase (cyclizing);

MeSH Related Number : 9054-75-5 (CAS RN);

Registry Number MeSH : EC 4.6.1.2;

Wikipedia link : https://en.wikipedia.org/wiki/Guanylate cyclase;

Is substance : O;

UNII : EC 4.6.1.2;

Details

Origin ID

D006162;

UMLS CUI

C0018358;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Atrial Natriuretic Peptide Receptor 1 [NCIt concept]
- NADPH-Cytochrome P450 Reductase [NCIt concept]
- natriuretic peptide receptor 1 [HGNC gene]
Currated CISMeF NLP mapping
- Guanylate Cyclase [NCIt concept]
- Guanylate cyclase (substance) [SNOMED CT concept]
- guanylate cyclase [SNOMED Notion]
Indexing information
- 1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one [MeSH Supplementary Concept]
- 3-(2-(2,2-dimethylpropylsulfanyl)pyridin-3-yl)-N-(3-hydroxycyclohexyl)acrylamide [MeSH Supplementary Concept]
- 3-(2-(4-chlorophenylsulfanyl)phenyl)-N-(4-dimethylaminobutyl)acrylamide [MeSH Supplementary Concept]
- 3-(4-Amino-5-cyclopropylpyrimidine-2-yl)-1-(2-fluorobenzyl)-1H-pyrazolo(3,4-b)pyridine [MeSH Supplementary Concept]
- 3-(5'-hydroxymethyl-2'-furyl)-1-benzylindazole [MeSH Supplementary Concept]
- 5-(3-bromophenyl)-1,3-dimethyl-5,11-dihydro-1H-indeno(2',1'-5,6)pyrido(2,3-d)pyrimidine-2,4,6-trione [MeSH Supplementary Concept]
- 5-chloro-2-(5-chlorothiophene-2-sulfonylamino)-N-(4-(morpholine-4-sulfonyl)phenyl)benzamide [MeSH Supplementary Concept]
- 6-anilino-5,8-quinolinedione [MeSH Supplementary Concept]
- BAY 58-2667 [MeSH Supplementary Concept]
- BAY 60-4552 [MeSH Supplementary Concept]
- CFM 1571 [MeSH Supplementary Concept]
- NS 2028 [MeSH Supplementary Concept]
- guanyl cyclase-B receptor [MeSH Supplementary Concept]
- guanylate cyclase-inhibitory protein, xenopus [MeSH Supplementary Concept]
- riociguat [MeSH Supplementary Concept]
Record concept(s)
- guanylate cyclase [MeSH concept]
Related MeSH Supplementary Concept(s)
- CARD11 protein, human [MeSH Supplementary Concept]
- CARD14 protein, human [MeSH Supplementary Concept]
- DdGCA protein, dictyostelium discoideum [MeSH Supplementary Concept]
- GC-G protein, mouse [MeSH Supplementary Concept]
- GCY-18 protein, C elegans [MeSH Supplementary Concept]
- GCY-23 protein, C elegans [MeSH Supplementary Concept]
- GCY-28 protein, C elegans [MeSH Supplementary Concept]
- GCY-35 protein, C elegans [MeSH Supplementary Concept]
- GCY-36 protein, C elegans [MeSH Supplementary Concept]
- GCY-8 protein, C elegans [MeSH Supplementary Concept]
- GUCD1 protein, human [MeSH Supplementary Concept]
- GUCY2F protein, human [MeSH Supplementary Concept]
- Gucy2d protein, mouse [MeSH Supplementary Concept]
- Gucy2d protein, rat [MeSH Supplementary Concept]
- Gucy2e protein, mouse [MeSH Supplementary Concept]
- Gucy2e protein, rat [MeSH Supplementary Concept]
- Gucy2f protein, mouse [MeSH Supplementary Concept]
- Gucy2f protein, rat [MeSH Supplementary Concept]
- Gyc76C protein, Drosophila [MeSH Supplementary Concept]
- ODR-1 protein, C elegans [MeSH Supplementary Concept]
- SgcA protein, dictyostelium discoideum [MeSH Supplementary Concept]
- Vari protein, Drosophila [MeSH Supplementary Concept]
- daf-11 protein, C elegans [MeSH Supplementary Concept]
- guanylate cyclase 1 [MeSH Supplementary Concept]
- gucy2d protein, zebrafish [MeSH Supplementary Concept]
- mpp5a protein, zebrafish [MeSH Supplementary Concept]
- resact protein, sea urchin [MeSH Supplementary Concept]
See also (suggested by CISMeF)
- plecanatide [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Guanylate Cyclase [NCIt concept]
- Guanylate cyclase (substance) [SNOMED CT concept]
- guanylate cyclase [SNOMED Notion]

Keyword's position in hierarchy(ies) :

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