NPC1-Like Intracellular Cholesterol Transporter 1

Preferred Label : NPC1-Like Intracellular Cholesterol Transporter 1;

NCIt synonyms : Niemann-Pick C1-Like Protein 1; NPC1L1; NPC1 Like Intracellular Cholesterol Transporter 1;

NCIt definition : NPC1-like intracellular cholesterol transporter 1 (1359 aa, 149 kDa) is encoded by the human NPC1L1 gene. This protein is a multipass transmembrane protein and plays a role in cholesterol and lipid homeostasis.;

Details

Origin ID

C74462;

UMLS CUI

C2698466;

OMIM relation
- Npc1-like 1 [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- NPC1L1 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cholesterol Homeostasis [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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