Interleukin-17 Receptor A

Preferred Label : Interleukin-17 Receptor A;

NCIt synonyms : IL-17 Receptor A; CD217; IL17RA; IL-17RA; CDw217; Antigen CD217; CD217 Antigen; Interleukin 17 Receptor A;

NCIt definition : Interleukin-17 receptor A (866 aa, 96 kDa) is encoded by the human IL17RA gene. This protein plays a role in immune responses mediated by interleukin-17A and -17F.;

NCIt note : Binding of homodimers of either interleukin-17A (IL17A) or (IL17F) or IL17A/IL17F heterodimers induces homodimerization of IL17RA with IL17RC. Monomeric IL17RA can also bind IL17F homodimers. Finally, IL17RA can form heterodimers with IL17RE, which can. bind to IL17C (UniProt);

Details

Origin ID

C179688;

UMLS CUI

C0669927;

Automatic exact mappings (from CISMeF team)
- Interleukin 17 receptor a [OMIM gene]
- interleukin 17 receptor A [ORDO Gene]
- interleukin 17 receptor A [HGNC gene]
- receptors, Interleukin-17 [MeSH concept]
- receptors, interleukin-17 [MeSH Descriptor]
Currated CISMeF NLP mapping
- Interleukin-17 receptor A [MeSH concept]
OMIM relation
- Interleukin 17 receptor a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- IL17RA protein, human [MeSH Supplementary Concept]
- IL17RA protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- IL17RA Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients