Antiviral Innate Immune Response Receptor RIG-I

Preferred Label : Antiviral Innate Immune Response Receptor RIG-I;

NCIt synonyms : Retinoic Acid-Inducible Gene 1 Protein; RIG-1; EC 3.6.4.13; RNA Helicase RIG-I; DEAD Box Protein 58; RIG-I; Retinoic Acid-Inducible Gene I Protein; RLR-1; RIG-I-Like Receptor 1; Probable ATP-Dependent RNA Helicase DDX58; DDX58; RIGI; RNA Sensor RIG-I; ATP-Dependent RNA Helicase DDX58;

NCIt definition : Antiviral innate immune response receptor RIG-I (925 aa, 107 kDa) is encoded by the human RIGI gene. This protein is involved in the activation of antiviral responses.;

Details

Origin ID

C101421;

UMLS CUI

C1310468;

OMIM relation
- Dexd/h-box helicase 58 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- RIGI protein, human [MeSH concept]
- RIGI protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Helicase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- RIGI Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Cytoskeleton [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytosolic DNA-Sensing Pathway [NCIt concept]
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Antiviral Response [NCIt concept]
- Hydrolysis [NCIt concept]
- Immune Response Process [NCIt concept]
- Immunity [NCIt concept]
- Ligand Binding [NCIt concept]
- Nucleic Acid Binding [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Processing [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transcriptional Activation [NCIt concept]
- Translation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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