Calmodulin - CISMeF

Preferred Label : Calmodulin;

NCIt synonyms : CALM; CALM2; Calmodulin 1; Calmodulin 1 (Phosphorylase Kinase, Delta); CAM1; CaM; CALM1; Phosphorylase Kinase, Delta Subunit;

NCIt definition : Calmodulin (149 aa, 17 kDa) is encoded by the human CALM1, CALM2 and CALM3 genes. This protein plays a role in the regulation of a number of enzymes, ion channels and signaling pathways.;

NCIt note : A heat-stable, low-molecular-weight activator protein found mainly in the brain and heart. The binding of calcium ions to this protein allows this protein to bind to cyclic nucleotide phosphodiesterases and to adenyl cyclase with subsequent activation. Thereby this protein modulates cyclic AMP and cyclic GMP levels.;

Details

Origin ID

C16375;

UMLS CUI

C1366910;

Automatic exact mappings (from CISMeF team)
- Calmodulin 1 [OMIM gene]
- Calmodulin 2 [OMIM gene]
- Cataract 5, multiple types [OMIM Phenotype]
- Cell adhesion molecule [FMA entity]
- Cerebrofacial arteriovenous metameric syndrome [ICD-11 More detail]
- KRIT1 ankyrin repeat containing [ORDO Gene]
- Phosphatidylinositol-binding clathrin assembly protein [OMIM gene]
- calmodulin 1 [HGNC gene]
- calmodulin 1 [ORDO Gene]
- calmodulin 2 [ORDO Gene]
- calmodulin 2 [HGNC gene]
- calmodulin 3 [ORDO Gene]
- calmodulin 3 [HGNC gene]
- complementary and integrative medicine [MedlinePlus Topic]
- complementary medicine [Q-code]
- complementary therapies [MeSH Descriptor]
- phosphatidylinositol binding clathrin assembly protein [ORDO Gene]
Currated CISMeF NLP mapping
- Calmodulin [FMA entity]
- calmodulin [MeSH Descriptor]
- calmodulin [MeSH concept]
- calmodulin [SNOMED Notion]
False automatic mappings
- Calming (procedure) [SNOMED CT concept]
- Calmodulin (substance) [SNOMED CT concept]
- Cerebral cavernous malformations [OMIM Phenotype]
- Cerebrofacial arteriovenous metameric syndrome [ORDO Disease]
- calmodulin (1-77) [MeSH concept]
- calmodulin (1-77) [MeSH Supplementary Concept]
- calmodulin (1-80) [MeSH concept]
- calmodulin (1-80) [MeSH Supplementary Concept]
- calmodulin (20-31) [MeSH concept]
- calmodulin (20-31) [MeSH Supplementary Concept]
- calmodulin (76-121) [MeSH concept]
- calmodulin (76-121) [MeSH Supplementary Concept]
- calmodulin (76-148) [MeSH concept]
- calmodulin (76-148) [MeSH Supplementary Concept]
- calmodulin (78-148) [MeSH concept]
- calmodulin (78-148) [MeSH Supplementary Concept]
- calmodulin (8-13) [MeSH concept]
- calmodulin (8-13) [MeSH Supplementary Concept]
OMIM relation
- Calmodulin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CALM1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Calcium-Binding Domain [NCIt concept]
- EF-Hand Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alzheimer's Disease Pathway KEGG [NCIt concept]
- BCR Immune Response Signaling Pathway [NCIt concept]
- Calcineurin-Regulated NFAT-Dependent Transcription Pathway [NCIt concept]
- Calcium Signaling in the CD4+ TCR Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Cellular Anthrax Toxin Pathway [NCIt concept]
- Downstream Signaling Pathway in Naive CD8+ T Cells [NCIt concept]
- Epidermal Growth Factor Receptor Downstream Signaling Pathway [NCIt concept]
- Gastric Acid Secretion Pathway [NCIt concept]
- Glioblastoma Multiforme Pathway [NCIt concept]
- Gonadotropin-Releasing Hormone Signaling Pathway [NCIt concept]
- Huntington's Disease Pathway [NCIt concept]
- IL2/PI3K Signaling Pathway [NCIt concept]
- Insulin-Mediated Glucose Transport Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Interferon-Gamma Signaling Pathway [NCIt concept]
- Lissencephaly-1 Gene in Neuronal Migration and Development [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Melanogenesis Pathway [NCIt concept]
- N-Cadherin Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
- Olfactory Transduction Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- Phosphatidylinositol Signaling System Pathway [NCIt concept]
- Phototransduction Pathway [NCIt concept]
- Regulation of Cytoplasmic and Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
- Salivary Secretion Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
- p38 MAPK Signaling Pathway PID [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Cell Cycle Process [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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