" /> Integrin Alpha-V - CISMeF





Preferred Label : Integrin Alpha-V;

NCIt synonyms : ITGAV Protein; Vitronectin Receptor Alpha Subunit CD51 Antigen; CD51 Antigen; Vitronectin Receptor Subunit Alpha; Integrin Alpha V;

NCIt definition : Integrin alpha-V (1148 aa, 116 kDa) is encoded by the human ITGAV gene. This protein plays a role in cell-matrix adhesion and pathological angiogenesis.;

NCIt note : Human integrin alpha-V protein is a type I membrane protein that forms a heterodimer with an integrin beta protein (either the beta-1, 3, 5, 6 or 8 polypeptide). The resulting complex binds to the tripeptide R-G-D, an amino acid sequence present in a number of ligands including vitronectin, fibronectin, fibrinogen, and laminin. Ligand binding regulates cell adhesion, growth and migration.;

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31/07/2025


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