Integrin AlphaV/Beta6

Preferred Label : Integrin AlphaV/Beta6;

NCIt synonyms : AlphaV/Beta6; AlphaV-Beta6; Alpha-V Beta-6; Alpha-V Beta-6 Integrin; Alpha(V)Beta(6) Integrin; Integrin AlphaV Beta6; Alpha-VBeta-6; Alpha-V/Beta-6; Integrin aVb6; Integrin AlphaV-Beta6; Integrin Alpha-V Beta-6; AlphaV Beta6; Integrin Alpha-VBeta-6; aVb6; Integrin-aVBeta6; Integrin alpha (V) beta (6); Alpha-V/Beta-6 Integrin; Integrin Alpha-V Beta-6 Protein; Integrin Alpha-V/Beta-6;

NCIt definition : Integrin alphaV/beta6 is a protein complex comprised of a heterodimer of integrin alpha-V and integrin beta-6. This complex plays a role in cell-matrix adhesion and viral entry.;

NCIt note : Integrin alphaV/beta6 binds to the amino acid sequence -R-G-D- in fibronectin and cytotactin and acts as a receptor for herpes simplex virus-1 (HHV-1); coxsackievirus A9, and coxsackievirus B1. (UniProt);

Details

Origin ID

C124258;

UMLS CUI

C0166814;

Automatic exact mappings (from CISMeF team)
- integrin alphavbeta6 [MeSH Supplementary Concept]
- integrin alphavbeta6 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- integrin alphavbeta6 [MeSH Supplementary Concept]
- integrin alphavbeta6 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Virus-Cell Membrane Interaction [NCIt concept]
has_gene_product_element
- Integrin Alpha-V [NCIt concept]
- Integrin Beta-6 [NCIt concept]
is_target
- Fluorine F 18 FP-R01-MG-F2 [NCIt concept]
- Fluorine F 18 alphaVbeta6-Binding Peptide [NCIt concept]
- Gallium Ga 68-labeled alphaVbeta6 Binding Peptide RAD 301 [NCIt concept]
- Interleukin-15 Fusion Protein BJ-001 [NCIt concept]
- Intetumumab [NCIt concept]
related_to_genetic_biomarker
- ITGAV Gene [NCIt concept]
- ITGB6 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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