Integrin AlphaV/Beta5

Preferred Label : Integrin AlphaV/Beta5;

NCIt synonyms : Integrin Alpha-V/Beta-5; Integrin-aVBeta5; Alpha-V/Beta-5 Integrin; Alpha-V/Beta-5; Integrin alpha (V) beta (5); Integrin Alpha-V Beta-5 Protein; Integrin aV/b5; aV/b5;

NCIt definition : Integrin alpha-V beta-5 is a heterodimeric protein with subunits designated alpha-V and beta-5. This complex is involved in both cellular adhesion, cell surface signaling, and angiogenesis.;

NCIt note : This protein dimer is a complex composed of one Integrin Alpha-V subunit and one Integrin Beta-5 subunit.;

Details

Origin ID

C53624;

UMLS CUI

C0083026;

Automatic exact mappings (from CISMeF team)
- integrin alphaVbeta5 [MeSH Supplementary Concept]
- integrin alphaVbeta5 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- integrin alphaVbeta5 [MeSH Supplementary Concept]
- integrin alphaVbeta5 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_affected_by_chemical_or_drug
- Cilengitide [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
has_gene_product_element
- Integrin Alpha-V [NCIt concept]
- Integrin Beta-5 [NCIt concept]
is_target
- Cilengitide [NCIt concept]
- Gallium Ga 68 FF58 [NCIt concept]
- Integrin Receptor Antagonist GLPG0187 [NCIt concept]
- Interleukin-15 Fusion Protein BJ-001 [NCIt concept]
- Internalized-arginylglycylaspartic Acid Cyclic Peptide [NCIt concept]
- Intetumumab [NCIt concept]
- Recombinant Vaccinia-MUC-1 Vaccine [NCIt concept]
related_to_genetic_biomarker
- ITGAV Gene [NCIt concept]
- ITGB5 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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