Integrin AlphaV/Beta8

Preferred Label : Integrin AlphaV/Beta8;

NCIt synonyms : Integrin-aVBeta8; AlphaV/Beta8; Alpha-V Beta-8 Integrin; AlphaV-Beta8; Alpha-V Beta-8; Alpha(V)Beta(8) Integrin; Integrin AlphaV Beta8; Alpha-VBeta-8; Alpha-V/Beta-8 Integrin; Alpha-V/Beta-8; Integrin aVb8; Integrin alpha (V) beta (8); Integrin AlphaV-Beta8; Integrin Alpha-V Beta-8; Integrin Alpha-V Beta-8 Protein; Integrin Alpha-V/Beta-8; AlphaV Beta8; Integrin Alpha-VBeta-8; aVb8;

NCIt definition : Integrin alphaV/beta8 is a protein complex comprised of a heterodimer of integrin alpha V and integrin beta 8. This complex is involved in the modulation of transforming growth factor-beta latency and fibronectin binding.;

NCI Metathesaurus CUI : CL1643198;

Details

Origin ID

C177542;

UMLS CUI

C5447841;

Automatic exact mappings (from CISMeF team)
- integrin alphavbeta8 [MeSH Supplementary Concept]
- integrin alphavbeta8 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Virus-Cell Membrane Interaction [NCIt concept]
has_gene_product_element
- Integrin Alpha-V [NCIt concept]
- Integrin Beta-8 [NCIt concept]
is_target
- Alpha V Beta 8 Antagonist PF-06940434 [NCIt concept]
related_to_genetic_biomarker
- ITGAV Gene [NCIt concept]
- ITGB8 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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