Integrin Beta-8

Preferred Label : Integrin Beta-8;

NCIt synonyms : Integrin Subunit Beta 8; Integrin Beta8; ITGB8; Integrin Beta 8;

NCIt definition : Integrin beta-8 (769 aa, 86 kDa) is encoded by the human ITGB8 gene. This protein plays a role in the regulation of transforming growth factor-beta activation and cell adhesion to fibronectin.;

NCI Metathesaurus CUI : CL1637622;

Details

Origin ID

C177541;

UMLS CUI

C5444331;

OMIM relation
- Integrin, beta-8 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGB8 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Integrin [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
gene_product_is_physical_part_of
- Integrin AlphaV/Beta8 [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Therapeutic Breast/Ovarian/Prostate Peptide Cancer Vaccine DPX-0907 [NCIt concept]

Keyword's position in hierarchy(ies) :

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