Integrin AlphaV/Beta1

Preferred Label : Integrin AlphaV/Beta1;

NCIt synonyms : Alpha-V Beta-1; Integrin alpha (V) beta (1); Alpha(V)Beta(1) Integrin; Integrin AlphaV Beta1; Integrin Alpha-V/Beta-1; Alpha-V Beta-1 Integrin; Integrin aVb1; Integrin Alpha-VBeta-1; aVb1; Integrin AlphaV-Beta1; Integrin Alpha-V Beta-1; AlphaV/Beta1; Integrin Alpha-V Beta-1 Protein;

NCIt definition : Integrin alphaV/beta1 is a protein complex comprised of a heterodimer of integrin alpha V and integrin beta 1. This complex is involved in the modulation of transforming growth factor-beta latency and binding to fibronectin, osteopontin and neural cell adhesion molecule L1 (CD171; L1).;

NCI Metathesaurus CUI : CL1647573;

Details

Origin ID

C177732;

UMLS CUI

C5557493;

Automatic exact mappings (from CISMeF team)
- integrin alphavbeta1 [MeSH Supplementary Concept]
- integrin alphavbeta1 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Ligand Binding [NCIt concept]
has_gene_product_element
- Integrin Alpha-V [NCIt concept]
- Integrin Beta-1 [NCIt concept]
is_target
- Intetumumab [NCIt concept]
related_to_genetic_biomarker
- ITGAV Gene [NCIt concept]
- ITGB1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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