Integrin Beta-1

Preferred Label : Integrin Beta-1;

NCIt synonyms : CD29 Antigen; VLA-4 Subunit Beta; CD29; Fibronectin Receptor Subunit Beta; Antigen CD29; GPIIA; Glycoprotein IIa; ITGB1;

NCIt definition : Integrin beta-1 (798 aa, 88 kDa) is encoded by the human ITGB1 gene. This protein plays a role in leukocyte migration, signal transduction, ligand binding and cell adhesion.;

Details

Origin ID

C96911;

UMLS CUI

C5391567;

Currated CISMeF NLP mapping
- CD29 [LOINC component]
- Integrin beta1 [MeSH Descriptor]
- Integrin beta1 [MeSH concept]
OMIM relation
- Integrin, beta-1 [OMIM gene]
See also inter- (CISMeF)
- Cluster of differentiation antigen 29 (substance) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- Itgb1 protein, human [MeSH Supplementary Concept]
Validated automatic mappings to BTNT
- lymphocyte antigen cdw29 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGB1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Alpha4/Beta1 and Alpha4/Beta7 Integrin Signaling Pathway [NCIt concept]
- Alpha6/Beta1 and Alpha6/Beta4 Integrin Signaling Pathway [NCIt concept]
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Axon Guidance Pathway [NCIt concept]
- Bacterial Invasion of Epithelial Cell Pathway [NCIt concept]
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Leukocyte Transendothelial Migration Pathway [NCIt concept]
- PTP4A Family Signaling Pathway [NCIt concept]
- Pathogenic Escherichia coli Infection Pathway [NCIt concept]
- Paxillin-Dependent Alpha4/Beta1 Integrin Signaling Pathway [NCIt concept]
- Paxillin-Independent Alpha4/Beta1 and Alpha4/Beta7 Integrin Signaling Pathway [NCIt concept]
- Reelin Signaling Pathway PID [NCIt concept]
- Shigellosis Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
- Syndecan-2-Mediated Signaling Pathway [NCIt concept]
- Syndecan-4-Mediated Signaling Pathway [NCIt concept]
gene_product_is_physical_part_of
- Integrin [NCIt concept]
- Integrin Alpha4/Beta1 [NCIt concept]
- Integrin Alpha5/Beta1 [NCIt concept]
- Integrin AlphaV/Beta1 [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Coagulation Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-integrin Beta-1 Monoclonal Antibody OS2966 [NCIt concept]

Keyword's position in hierarchy(ies) :

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