Integrin Alpha5/Beta1

Preferred Label : Integrin Alpha5/Beta1;

NCIt synonyms : Alpha-5 Beta-1; Integrin alpha (5) beta (1); Integrin Alpha5 Beta1; Alpha(5)Beta(1) Integrin; Integrin Alpha-5/Beta-1; Alpha-5 Beta-1 Integrin; Integrin a5b1; Integrin Alpha-5Beta-1; a5b1; Integrin Alpha5-Beta1; Integrin Alpha-5 Beta-1; Alpha5/Beta1; Integrin Alpha-5 Beta-1 Protein;

NCIt definition : Integrin alpha5/beta1 is a protein complex comprised of a heterodimer of integrin alpha 5 and integrin beta 1. This complex is involved in the modulation of transforming growth factor-beta latency and binding to fibronectin, osteopontin, fibrillin, thrombospondin and neural cell adhesion molecule L1 (CD171; L1).;

NCI Metathesaurus CUI : CL1647574;

Details

Origin ID

C177733;

UMLS CUI

C1138422;

Automatic exact mappings (from CISMeF team)
- integrin alpha5beta1 [MeSH Descriptor]
- integrin alpha5beta1 [MeSH concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- integrin alpha5beta1 [MeSH Descriptor]
- integrin alpha5beta1 [MeSH concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Adhesion Molecule [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Cell-Matrix Adhesion Process [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Leukocyte Trafficking [NCIt concept]
- Ligand Binding [NCIt concept]
has_gene_product_element
- Integrin Beta-1 [NCIt concept]
is_target
- Anti-A5B1 Integrin Monoclonal Antibody PF-04605412 [NCIt concept]
- Anti-alpha5beta1 Integrin Antibody MINT1526A [NCIt concept]
- Recombinant Bacterial Minicells VAX014 [NCIt concept]
related_to_genetic_biomarker
- ITGA5 Gene [NCIt concept]
- ITGB1 Gene [NCIt concept]

Keyword's position in hierarchy(ies) :

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