Amyloid Protein-Binding Protein 2

Preferred Label : Amyloid Protein-Binding Protein 2;

NCIt synonyms : Protein Interacting with APP Tail 1; Amyloid Beta Precursor Protein (Cytoplasmic Tail) Binding Protein 2; PAT1 Protein; APPBP2; Amyloid Beta Precursor Protein-Binding Protein 2; APP-BP2;

NCIt definition : Amyloid protein-binding protein 2 (585 aa, 67 kDa) is encoded by the human APPBP2 gene. This protein plays a role in subcellular protein localization.;

NCIt note : Cell surface sorting of the signal-transducing APP depends on a cytoplasmic tyrosine-based basolateral sorting signal (BaSS) sequence to which APPBP2 specifically binds.;

Details

Origin ID

C21486;

UMLS CUI

C1332256;

OMIM relation
- Amyloid beta precursor protein-binding protein 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_encodes_gene_product
- APPBP2 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cytoplasm [NCIt concept]
- Golgi Apparatus [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Globular Region [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- PKC Phosphorylation Site [NCIt concept]
- Tetratricopeptide Repeat [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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