Calcium Homeostasis Modulator Protein 1

Preferred Label : Calcium Homeostasis Modulator Protein 1;

NCIt synonyms : CALHM1; Protein FAM26C;

NCIt definition : Calcium homeostasis modulator protein 1 (346 aa, 38 kDa) is encoded by the human CALHM1 gene. This protein is involved in the regulation of processing of amyloid-beta precursor protein and in voltage-gated and calcium-activated ion channel that promotes release of ATP from cells residing in taste buds.;

NCIt note : Calcium homeostasis modulator protein 1 forms a fast-activating voltage-gated ATP-release channel with calcium homeostasis modulator protein 3 in type II taste bud cells. (UniProt);

Details

Origin ID

C204116;

UMLS CUI

C2355039;

OMIM relation
- Calcium homeostasis modulator 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CALHM1 protein, human [MeSH Supplementary Concept]
- CALHM1 protein, human [MeSH concept]
gene_encodes_gene_product
- CALHM1 Gene [NCIt concept]
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Brain [NCIt concept]
- Circumvallate Papilla [NCIt concept]
gene_product_has_associated_anatomy
- Calcium Channel [NCIt concept]
- Cellular Membrane [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Membrane of the Endoplasmic Reticulum [NCIt concept]
- Plasma Membrane [NCIt concept]
- Type II Epithelial Receptor Cell [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Taste Transduction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Homeostasis [NCIt concept]
- Gustation [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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