S100 Calcium Binding Protein

Preferred Label : S100 Calcium Binding Protein;

NCIt synonyms : S-100 Protein; S100 Protein;

NCIt related terms : S100;

NCIt definition : A family of low molecular weight proteins that are characterized by the presence of two EF-hand calcium binding domains. These proteins form homodimers that localize either in the cytoplasm or nucleus of neural crest-derived cells and are involved in the regulation of many cellular processes such as cell cycle progression and differentiation.;

NCIt note : The name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH.;

Details

Origin ID

C29924;

UMLS CUI

C0027758;

Automatic exact mappings (from CISMeF team)
- S-100 Ag [LOINC component]
- S100 calcium binding protein B [LOINC component]
- S100 proteins [MeSH concept]
- s100 proteins [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- S-100 Ag [LOINC component]
- S-100 Ag [LOINC component]
- S100 proteins [MeSH concept]
- s100 proteins [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- EWS Authorized Value Terminology [NCIt concept]
- EWS Immunohistochemistry Table [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- S100 Family Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Calcium-Binding Domain [NCIt concept]
- EF-Hand Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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