Sialoadhesin - CISMeF

Preferred Label : Sialoadhesin;

NCIt synonyms : CD169; SIGLEC1; Siglec-1; Sialic Acid Binding Ig Like Lectin 1; Sialic Acid-Binding Ig-Like Lectin 1; CD169 Antigen; Sialic Acid-Binding Immunoglobulin-Like Lectin 1;

NCIt definition : Sialoadhesin (1709 aa, 183 kDa) is encoded by the human SIGLEC1 gene. This protein plays a role in binding to sialic acid that mediates cell-cell adhesion in leukocytes and host cell binding to and endocytosis of viruses.;

Details

Origin ID

C207886;

OMIM relation
- Sialic acid-binding immunoglobulin-like lectin 1 [OMIM gene]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- SIGLEC1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Macrophage [NCIt concept]
- Membrane of the Endosome [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Immunoglobulin Family Protein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Immunoglobulin-Like V-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Ligand Binding [NCIt concept]
- Signal Transduction [NCIt concept]
- Virus-Cell Membrane Interaction [NCIt concept]

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