Integrin Beta-4

Preferred Label : Integrin Beta-4;

NCIt synonyms : ITGB4; CD104 Antigen; GP150;

NCIt definition : Integrin beta-4 (1822 aa, 202 kDa) is encoded by the human ITGB4 gene. This protein is involved in epithelial cell adhesion.;

NCIt note : The integrin alpha-6/beta-4, a receptor for the laminins, is likely to play a pivotal role in the biology of invasive carcinoma.;

Details

Origin ID

C28490;

UMLS CUI

C0637379;

OMIM relation
- Integrin, beta-4 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- ITGB4 protein, human [MeSH concept]
- ITGB4 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGB4 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
gene_product_is_physical_part_of
- Integrin [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Histogenic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients