Microsomal Triglyceride Transfer Protein Large Subunit

Preferred Label : Microsomal Triglyceride Transfer Protein Large Subunit;

NCIt synonyms : MTTP;

NCIt definition : Microsomal triglyceride transfer protein large subunit (894 aa, 99 kDa) is encoded by the human MTTP gene. This protein plays a role in the targeting of triglycerides, cholesteryl esters, and phospholipids to membranes or vesicles.;

NCIt note : Microsomal triglyceride transfer protein large subunit is part of the heterodimeric microsomal triglyceride transfer protein. The small subunit of the transfer protein is protein disulfide-isomerase.;

NCI Metathesaurus CUI : CL473851;

Details

Origin ID

C116416;

UMLS CUI

C1741347;

OMIM relation
- Microsomal triglyceride transfer protein [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MTTP protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- MTTP Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Endoplasmic Reticulum [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Lipid Binding [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Lipid Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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