Tandem Chimeric Antigen Receptor

Preferred Label : Tandem Chimeric Antigen Receptor;

NCIt synonyms : Bispecific CAR; Dual-Targeted Chimeric Antigen Receptor; Tandem CAR; Dual-Targeted CAR; Bispecific Chimeric Antigen Receptor;

NCIt related terms : Tandem;

NCIt definition : A chimeric antigen receptor engineered to with two antigen domains linked consecutively, designed to target two distinct tumor antigens.;

NCI Metathesaurus CUI : CL1412943;

Details

Origin ID

C175586;

UMLS CUI

C5444302;

Automatic exact mappings (from CISMeF team)
- Pedal- or hand-propelled cycles, other and unspecified [ICHI extension code]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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