Hepatocyte Nuclear Factor 4-Alpha

Preferred Label : Hepatocyte Nuclear Factor 4-Alpha;

NCIt synonyms : HNF4A; HNF-4-Alpha; TCF-14; NR2A1; Nuclear Receptor Subfamily 2 Group A Member 1; Transcription Factor HNF-4; HNF4-Alpha; Transcription Factor 14; Hepatocyte Nuclear Factor 4 Alpha;

NCIt definition : Hepatocyte nuclear factor 4-alpha (474 aa, 53 kDa) is encoded by the human HNF4A gene. This protein plays a role in the transcriptional regulation of genes involved in hepatocyte differentiation.;

Details

Origin ID

C201745;

OMIM relation
- Hepatocyte nuclear factor 4-alpha [OMIM gene]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- HNF4A Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Nuclear Receptor Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
- Transcription Factor Gene [NCIt concept]
- Transcription Regulation Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- Hormone Receptor [NCIt concept]
- Sequence-Specific DNA Binding Protein [NCIt concept]
gene_product_has_chemical_classification
- Nuclear Hormone Receptor Superfamily [NCIt concept]
gene_product_has_structural_domain_or_motif
- Hormone Receptor DNA-Binding Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- FOXA2 and FOXA3 Transcription Factor Signaling Pathway [NCIt concept]
- HIF-1-Alpha Transcription Factor Pathway [NCIt concept]
- Maturity Onset Diabetes of the Young Pathway [NCIt concept]
- Regulation of Nuclear SMAD2/3 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biological Rhythm [NCIt concept]
- Cell Differentiation Process [NCIt concept]
- Cell Proliferation [NCIt concept]
- DNA Binding [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Maturation [NCIt concept]
- Organogenesis [NCIt concept]
- Pattern Formation [NCIt concept]
- Phospholipid Metabolism [NCIt concept]
- Receptor Signaling [NCIt concept]
- Transcriptional Regulation [NCIt concept]
- Triglyceride Metabolism [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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