Sodium/Glucose Cotransporter 2

Preferred Label : Sodium/Glucose Cotransporter 2;

NCIt synonyms : Na( )/Glucose Cotransporter 2; Low Affinity Sodium-Glucose Cotransporter; Solute Carrier Family 5 Member 2; SGLT2; SLC5A2;

NCIt definition : Sodium/glucose cotransporter 2 (672 aa, 73 kDa) is encoded by the human SLC5A2 gene. This protein is involved in sodium/glucose symport.;

Details

Origin ID

C119006;

UMLS CUI

C1505133;

Automatic exact mappings (from CISMeF team)
- Sodium-Glucose transporter 2 [MeSH Descriptor]
- Solute carrier family 5 (sodium/glucose cotransporter), member 2 [OMIM gene]
- solute carrier family 2 member 5 [HGNC gene]
- solute carrier family 5 member 2 [HGNC gene]
- solute carrier family 5 member 2 [ORDO Gene]
OMIM relation
- Solute carrier family 5 (sodium/glucose cotransporter), member 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC5A2 protein, human [MeSH Supplementary Concept]
- SLC5A2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC5A2 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Renal Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
is_target
- Canagliflozin [NCIt concept]
- Dapagliflozin [NCIt concept]
- Dapagliflozin Propanediol [NCIt concept]
- Empagliflozin [NCIt concept]
- SGLT2 Inhibitor [NCIt concept]

Keyword's position in hierarchy(ies) :

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