Dapagliflozin - CISMeF

Preferred Label : Dapagliflozin;

NCIt synonyms : D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1S)-, Compd. with (2S)-1,2-propanediol, Hydrate (1:1:1);

NCIt definition : A selective sodium-glucose co-transporter subtype 2 (SGLT2) inhibitor with antihyperglycemic activity. Dapagliflozin selectively and potently inhibits SGLT2 compared to SGLT1, which is the cotransporter of glucose in the gut.;

UNII : 1ULL0QJ8UC;

InChIKey : JVHXJTBJCFBINQ-ADAARDCZSA-N;

CAS number : 461432-26-8; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 461432-26-8 alt lien vers site G-SRS target _blank img src /img/logos/logo_g-srs.png alt Logo G-SRS /a ;

Molecule name : BMS-512148-05;

Chemical formula : C21H25ClO6;

Details

Origin ID

C78126;

UMLS CUI

C2353951;

Automatic exact mappings (from CISMeF team)
- Dapagliflozin [ICD-11 Extension code]
CISMeF manual mappings
- DAPAGLIFLOZIN [Drug component]
- Dapagliflozin (substance) [SNOMED CT concept]
Currated CISMeF NLP mapping
- dapagliflozin [MeSH concept]
- dapagliflozin [MeSH Supplementary Concept]
See also inter- (CISMeF)
- Product containing dapagliflozin (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Organic Chemical [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Dapagliflozin (substance) [SNOMED CT concept]
- Product containing dapagliflozin (medicinal product) [SNOMED CT concept]
- dapagliflozin [ATC Code]
- dapagliflozin [MeSH Supplementary Concept]
- dapagliflozin [MeSH concept]
Validated automatic mappings to BTNT
- dapagliflozin [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
- NCIt COVID-19 Agent Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
has_target
- Sodium/Glucose Cotransporter 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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