Coagulation Factor VIII

Preferred Label : Coagulation Factor VIII;

NCIt synonyms : Coagulation Factor VIIIc; F8; Factor VIII F8B; Antihaemophilic Factor; Procoagulant Component; Antihemophilic Factor; AHF; Coagulation Factor-VIII;

NCIt related terms : FVIII; Factor VIII;

NCIt definition : Coagulation factor VIII (2351 aa, 267 kDa) is encoded by the human F8 gene. This protein plays a role in the modulation of coagulation factor IX activity and blood coagulation.;

Alternative definition : CDISC: An antigen encoded by the F8 gene and plays a role in the modulation of coagulation factor VIII activity and blood coagulation.;

Details

Origin ID

C16571;

UMLS CUI

C1307126;

Automatic exact mappings (from CISMeF team)
- Antihemophilic factor [ICHI extension code]
- Antihemophilic globulin [FMA entity]
- Argentinian haemorrhagic fever [ICD-11 Subcategory]
- Coagulation factor VII level [MedDRA Preferred Term]
- Coagulation factor VII level low [MedDRA LLT]
- Coagulation factor VIII [OMIM gene]
- Coagulation factor VIII [ICD-11 Extension code]
- Coagulation factor VIII level low [MedDRA LLT]
- Factor VIII [PASCAL descriptor]
- Factor VIII given [LOINC component]
- Factor VIIIc (substance) [SNOMED CT concept]
- coagulation factor VIII [ORDO Gene]
- coagulation factor VIII [HGNC gene]
- coagulation factor viii [EMDN type]
- coagulation factor viii [medical devices type]
- factor VII [MeSH concept]
- factor VII [MeSH Descriptor]
- factor VIII [Blood Transfusion thesaurus concept]
- factor VIIa [MeSH concept]
Currated CISMeF NLP mapping
- Antihaemophilic factor [MedDRA LLT]
- Antihemophilic factor [ICD-11 Extension code]
- Antihemophilic factor [MedDRA LLT]
- Coagulation factor VIII (substance) [SNOMED CT concept]
- Coagulation factor VIII activity [LOINC component]
- Coagulation factor VIII level [MedDRA Preferred Term]
- F8 protein, human [MeSH Supplementary Concept]
- F8 protein, human [MeSH concept]
- Factor VIII [LOINC component]
- blood-coagulation factor viii [Substance BNPC]
- coagulation factor viii [SNOMED Notion]
- factor VIII [MeSH Descriptor]
- factor VIII [MeSH concept]
- factor VIII (des-797-1562) [MeSH concept]
- factor VIII (des-797-1562) [MeSH Supplementary Concept]
False automatic mappings
- factor VIIa [MeSH Descriptor]
OMIM relation
- Coagulation factor VIII [OMIM gene]
See also inter- (CISMeF)
- Coagulation factor VIII [LOINC component]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- F8 protein, human [MeSH concept]
- F8 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CDISC SDTM Binding Agent for Immunogenicity Tests Terminology [NCIt concept]
- CDISC SDTM Terminology [NCIt concept]
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- Clinical Data Interchange Standards Consortium Terminology [NCIt concept]
gene_encodes_gene_product
- Coagulation Factor Gene [NCIt concept]
- F8 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_biochemical_function
- Coagulation Factor [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Complement and Coagulation Cascade [NCIt concept]
- Intrinsic Prothrombin Activation Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Hemophilia A [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Binding [NCIt concept]
- Coagulation Process [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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