Thyroxine-Binding Globulin

Preferred Label : Thyroxine-Binding Globulin;

NCIt synonyms : T4-Binding Globulin; Serpin A7; Thyroxin-Binding Globulin; SERPINA7;

NCIt definition : Thyroxine-binding globulin (415 aa, 46 kDa) is encoded by the human SERPINA7 gene. This protein plays a role in both binding to and transport of both thyroxine and triiodothyroxine.;

NCIt note : Thyroxine-binding globulin appears to have no protease inhibitory activity. (EntrezGene);

Details

Origin ID

C106005;

UMLS CUI

C2713677;

Automatic exact mappings (from CISMeF team)
- Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 [ORDO Gene]
- Thyroxin binding globulin [MedDRA Preferred Term]
- Thyroxine binding globulin [LOINC component]
- Thyroxine binding globulin (substance) [SNOMED CT concept]
- Thyroxine binding globulin measurement (procedure) [SNOMED CT concept]
- Thyroxine-Binding globulin [MeSH concept]
- Thyroxine-binding globulin of serum [OMIM gene]
- serpin family A member 7 [HGNC gene]
- thyroxine-binding proteins [MeSH Descriptor]
OMIM relation
- Thyroxine-binding globulin of serum [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SERPINA7 protein, human [MeSH Supplementary Concept]
- SERPINA7 protein, human [MeSH concept]
Validated automatic mappings to NTBT
- Thyroxine-Binding globulin [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SERPINA7 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hepatic Tissue [NCIt concept]
- Plasma [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Extracellular Space [NCIt concept]
gene_product_has_chemical_classification
- Serpin [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Peptide Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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