" /> Insulin Receptor - CISMeF





Preferred Label : Insulin Receptor;

NCIt synonyms : INSR; CD220 Antigen; IR; Antigen CD220; EC 2.7.10.1; CD220;

NCIt definition : Insulin receptor (1382 aa, 156 kDa) is encoded by the human INSR gene. This protein plays a role in both signal transduction and glucose homeostasis.;

NCIt note : Insulin receptor is cleaved to generate and alpha chain and a beta chain. The mature receptor is a tetramer of 2 alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. (UniProt);

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31/07/2025


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