NCIt related terms : insulin glargine recombinant; Lantus;
NCIt definition : A recombinant human insulin analog with long-acting, blood glucose-lowering activity.
Insulin glargine, like regular types of human insulin, regulates glucose metabolism
by binding to insulin receptors on muscle and fat cells, thereby facilitating the
cellular uptake of glucose. This lowers blood glucose levels. At the same time, insulin
glargine inhibits the liver's conversion of stored glycogen into glucose, which also
contributes to lower blood glucose levels. Insulin glargine also inhibits lipolysis
in adipose tissue, inhibits proteolysis, and enhances protein synthesis. (NCI05);
Alternative definition : NCI-GLOSS: A drug used to control the amount of sugar in the blood of patients with
diabetes. It is a form of the hormone insulin that is made in the laboratory. Insulin
glargine controls blood sugar longer than insulin does. It is a type of therapeutic
insulin.;
UNII : 2ZM8CX04RZ;
CAS number : 160337-95-1; a href https://gsrs.ncats.nih.gov/ginas/app/beta/browse-substance?search 160337-95-1
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G-SRS /a ;
Drug name : Lantus;
Chemical formula : C267H404N72O78S6;
Codes from synonyms : CDR0000658820; CDR0000658817; CDR0000658818;