Insulin Glargine

Preferred Label : Insulin Glargine;

NCIt related terms : insulin glargine recombinant; Lantus;

NCIt definition : A recombinant human insulin analog with long-acting, blood glucose-lowering activity. Insulin glargine, like regular types of human insulin, regulates glucose metabolism by binding to insulin receptors on muscle and fat cells, thereby facilitating the cellular uptake of glucose. This lowers blood glucose levels. At the same time, insulin glargine inhibits the liver's conversion of stored glycogen into glucose, which also contributes to lower blood glucose levels. Insulin glargine also inhibits lipolysis in adipose tissue, inhibits proteolysis, and enhances protein synthesis. (NCI05);

Alternative definition : NCI-GLOSS: A drug used to control the amount of sugar in the blood of patients with diabetes. It is a form of the hormone insulin that is made in the laboratory. Insulin glargine controls blood sugar longer than insulin does. It is a type of therapeutic insulin.;

UNII : 2ZM8CX04RZ;

CAS number : 160337-95-1;

Drug name : Lantus;

Chemical formula : C267H404N72O78S6;

Codes from synonyms : CDR0000658820; CDR0000658817; CDR0000658818;

Détails

Origin ID

C47564;

UMLS CUI

C0907402;

CISMeF manual mappings
- Insulin Glargine [MeSH Descriptor]
See also inter- (CISMeF)
- Product containing insulin glargine (medicinal product) [SNOMED CT concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Hormone [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Insulin Glargine [MeSH Descriptor]
- Insulin Glargine [MeSH concept]
- Insulin glargine (substance) [SNOMED CT concept]
- Product containing insulin glargine (medicinal product) [SNOMED CT concept]
- insulin glargine [ATC Code]
Validated automatic mappings to BTNT
- insulin glargine [ATC Code]
concept_is_in_subset
- CTRP Agent Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- FDA Established Names and Unique Ingredient Identifier Codes Terminology [NCIt concept]
- NCI Drug Dictionary Terminology [NCIt concept]
has_target
- Insulin Receptor [NCIt concept]

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