Preferred Label : receptor, insulin;

MeSH definition : A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.;

MeSH synonym : receptors, insulin; insulin receptors; insulin-dependent tyrosine protein kinase; insulin receptor; insulin receptor protein-tyrosine kinase; insulin receptor protein tyrosine kinase;

CISMeF synonym : EC 2.7.1.112;

MeSH hyponym : insulin receptor beta subunit; insulin receptor alpha subunit; Insulin Receptor beta Chain; Insulin Receptor alpha Chain;

Registry Number MeSH : EC 2.7.10.1;

Wikipedia link : https://en.wikipedia.org/wiki/Insulin receptor;

Is substance : O;

UNII : EC 2.7.10.1;

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A cell surface receptor for INSULIN. It comprises a tetramer of two alpha and two beta subunits which are derived from cleavage of a single precursor protein. The receptor contains an intrinsic TYROSINE KINASE domain that is located within the beta subunit. Activation of the receptor by INSULIN results in numerous metabolic changes including increased uptake of GLUCOSE into the liver, muscle, and ADIPOSE TISSUE.

https://rmlg.uliege.be/article/1226
2005
Belgium
French
receptor, insulin
journal article
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27/07/2025


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