Chitinase-3-Like Protein 1

Preferred Label : Chitinase-3-Like Protein 1;

NCIt synonyms : YKL-40; Chondrocyte Protein YKL40; hCGP-39; 39 kDa Synovial Protein; GP-39; CGP-39; Cartilage Glycoprotein 39; CHI3L1;

NCIt definition : Chitinase-3-like protein 1 (383 aa, 43 kDa) is encoded by the human CHI3L1 gene. This protein plays a role in tissue remodeling, inflammation and chitin binding.;

Alternative definition : NCI-GLOSS: A substance that may be found in higher-than-normal amounts in the blood of patients with certain types of cancer and inflammatory diseases. It is a type of glycoprotein.;

NCIt note : Chitinase-3-like protein 1 does not possess chitinase activity. (UniProt);

Codes from synonyms : CDR0000549702;

Details

Origin ID

C93267;

UMLS CUI

C0528649;

OMIM relation
- Chitinase 3-like 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- CHI3L1 protein, human [MeSH Supplementary Concept]
- CHI3L1 protein, human [MeSH concept]
- YKL-40 [LOINC component]
gene_encodes_gene_product
- CHI3L1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hepatic Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Chondrocyte [NCIt concept]
- Cytoplasm [NCIt concept]
- Extracellular Space [NCIt concept]
- Macrophage [NCIt concept]
- Synovial Cell [NCIt concept]
gene_product_has_biochemical_function
- Lectin [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Histogenic Process [NCIt concept]
- Immune Response Process [NCIt concept]
- Inflammatory Response [NCIt concept]
- Ligand Binding [NCIt concept]

Keyword's position in hierarchy(ies) :

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