Cellular Retinoic Acid Binding Protein

Preferred Label : Cellular Retinoic Acid Binding Protein;

NCIt synonyms : CRABP;

NCIt definition : Cellular Retinoic Acid-Binding Proteins are assumed to play an important role in retinoic acid-mediated differentiation and proliferation processes. Cytoplasmic CRABP-I and CRABP-II may regulate access of retinoic acid to nuclear retinoic acid receptors. CRABP-II may participate in a regulatory feedback mechanism to control the action of retinoic acid on cell differentiation. CRABP-I and CRABP-II belong to the FABP/P2/CRBP/CRABP family of transporters. (from OMIM 180230, 180231, SWISS-PROT P29762, P29373, and NCI);

Details

Origin ID

C19818;

UMLS CUI

C0599344;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Retinoic Acid Binding [NCIt concept]
- Signal Transduction [NCIt concept]
is_chemical_classification_of_gene_product
- Cellular Retinoic Acid-Binding Protein 1 [NCIt concept]
- Cellular Retinoic Acid-Binding Protein 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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