Mucolipin-1 - CISMeF

Preferred Label : Mucolipin-1;

NCIt synonyms : Mucolipin TRP Cation Channel 1; Mucolipidin 1; ML1; MCOLN1; MG-2; Mucolipidin; TRPML1; Transient Receptor Potential Channel Mucolipin 1;

NCIt definition : Mucolipin-1 (580 aa, 65 kDa) is encoded by the human MCOLN1 gene. This protein is involved in nonselective, intra- and intercellular cation transport and the regulation of membrane trafficking events.;

NCIt note : Mucolipin-1 (MCOLN1) can form either homotetrameric channels or homooligomeric channels with MCOLN2 or MCOLN3. (UniProt);

Details

Origin ID

C203785;

UMLS CUI

C1431987;

OMIM relation
- Mucolipin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MCOLN1 protein, human [MeSH Supplementary Concept]
- MCOLN1 protein, human [MeSH concept]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- MCOLN1 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Calcium Channel [NCIt concept]
- Cellular Membrane [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Late Endosome [NCIt concept]
- Membrane of the Endosome [NCIt concept]
- Membrane of the Lysosome [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Lysosome Assembly Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Homeostatic Process [NCIt concept]
- Intracellular Transport [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Lipid Transport [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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