Interleukin-18 Receptor 1

Preferred Label : Interleukin-18 Receptor 1;

NCIt synonyms : IL1 Receptor-Related Protein; IL-18R1; CD218 Antigen-Like Family Member A; CD218a Antigen; IL-18R-1; IL1R-rp; IL-1Rrp; CD218a;

NCIt definition : Interleukin-18 receptor 1 (541 aa, 62 kDa) is encoded by the human IL18R1 gene. This protein is involved in both interleukin-18 binding and the regulation of NF-kB signaling.;

Details

Origin ID

C124084;

UMLS CUI

C4085191;

Automatic exact mappings (from CISMeF team)
- Interleukin 18 receptor 1 [OMIM gene]
- interleukin-18 receptor alpha subunit [MeSH Descriptor]
OMIM relation
- Interleukin 18 receptor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- IL18R1 Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- IL12 Signaling Pathway [NCIt concept]
- IL12/STAT4 Signaling Pathway [NCIt concept]
- IL23-Mediated Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients