Integrin Alpha-E

Preferred Label : Integrin Alpha-E;

NCIt synonyms : Mucosal Lymphocyte 1 Antigen; HML-1 Antigen; CD103 Antigen; Antigen CD103, Human Mucosal Lymphocyte Antigen 1; Alpha Polypeptide; Integrin Alpha-IEL;

NCIt related terms : CD103;

NCIt definition : Integrin alpha-E (1179 aa, 130 kDa) is encoded by the human ITGAE gene. This protein plays a role in cell adhesion and may be involved in activation of intestinal intraepithelial lymphocytes.;

Details

Origin ID

C107130;

UMLS CUI

C1141628;

Automatic exact mappings (from CISMeF team)
- CD103 [LOINC component]
- CD11c Ag [LOINC component]
- CD11c Antigen [MeSH Descriptor]
- Integrin, alpha-e [OMIM gene]
- alpha E integrins [MeSH concept]
- alpha E integrins [MeSH Supplementary Concept]
- integrin alpha chains [MeSH Descriptor]
- integrin alphaEbeta7 [MeSH Supplementary Concept]
- integrin subunit alpha E [HGNC gene]
OMIM relation
- Integrin, alpha-e [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- CD103 [LOINC component]
- ITGAE protein, human [MeSH concept]
- Lymphocyte antigen CD103 (substance) [SNOMED CT concept]
- lymphocyte antigen cd103 [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGAE Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Intraepithelial T-Lymphocyte [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Adherens Junction Formation Pathway [NCIt concept]
gene_product_is_physical_part_of
- Integrin [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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