Amiloride-Sensitive Sodium Channel Subunit Alpha

Preferred Label : Amiloride-Sensitive Sodium Channel Subunit Alpha;

NCIt synonyms : Nonvoltage-Gated Sodium Channel 1 Subunit Alpha; Epithelial Na( ) Channel Subunit Alpha; ENaCA; Alpha-ENaC; SCNEA; SCNN1A; Amiloride-Sensitive Epithelial Sodium Channel Alpha Subunit; Alpha-NaCH;

NCIt definition : Amiloride-sensitive sodium channel subunit alpha (669 aa, 76 kDa) is encoded by the human SCNN1A gene. This protein is involved in mediating sodium ion transport and in maintaining electrolyte, blood pressure and airway surface liquid homeostasis.;

NCIt note : Amiloride-sensitive sodium channel subunit alpha is part of the amiloride-sensitive sodium channel complex, which is a heterotrimer containing one alpha, one beta and one gamma subunit. (UniProt);

Details

Origin ID

C206397;

OMIM relation
- Sodium channel, epithelial 1, alpha subunit [OMIM gene]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- SCNN1A Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Cilium [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Plasma Membrane [NCIt concept]
- Sodium Channel [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aldosterone-Regulated Sodium Reabsorption Pathway [NCIt concept]
- Taste Transduction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Gustation [NCIt concept]
- Homeostatic Process [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

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