Sortilin - CISMeF

Preferred Label : Sortilin;

NCIt synonyms : 100 kDa NT Receptor; Neurotensin Receptor 3; Glycoprotein 95; NT3; SORT1; Gp95; NTR3;

NCIt definition : Sortilin (831 aa, 92 kDa) is encoded by the human SORT1 gene. This protein is involved in protein sorting, cholesterol homeostasis and neuropeptide signaling.;

Details

Origin ID

C178267;

UMLS CUI

C2603464;

Automatic exact mappings (from CISMeF team)
- Neurotrophin 3 [OMIM gene]
- Sortilin [OMIM gene]
OMIM relation
- Sortilin [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- SORT1 protein, human [MeSH concept]
Validated automatic mappings to BTNT
- SORT1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- SORT1 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysosome Assembly Pathway [NCIt concept]
- Nerve Growth Factor Receptor Signaling Pathway [NCIt concept]
- Neurotrophin Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cholesterol Homeostasis [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Subcellular Protein Targeting [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
is_target
- Sudocetaxel Zendusortide [NCIt concept]

Keyword's position in hierarchy(ies) :

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