Interleukin-7 Receptor Subunit Alpha

Preferred Label : Interleukin-7 Receptor Subunit Alpha;

NCIt synonyms : Interleukin 7 Receptor Alpha; CD127; IL7R; IL-7R-Alpha; IL-7RA; IL-7R Subunit Alpha; IL-7 Receptor Subunit Alpha; CDw127; Interleukin 7 Receptor; Interleukin-7 Receptor;

NCIt definition : Interleukin-7 receptor subunit alpha (459 aa, 52 kDa) is encoded by the human IL7R gene. This protein is involved in both interleukin binding and signal transduction.;

NCI Metathesaurus CUI : CL775331;

Details

Origin ID

C26278;

UMLS CUI

C4507561;

Currated CISMeF NLP mapping
- receptors, Interleukin-7 [MeSH concept]
- receptors, interleukin-7 [MeSH Descriptor]
False automatic mappings
- Interleukin-7 receptor (substance) [SNOMED CT concept]
OMIM relation
- Interleukin 7 receptor [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- IL7R protein, human [MeSH Supplementary Concept]
- Interleukin-7 receptor alpha subunit [MeSH concept]
- interleukin-7 receptor alpha subunit [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cytokine Receptor Gene [NCIt concept]
- IL7R Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- IL7 Signaling Pathway [NCIt concept]
- Jak-STAT Signaling Pathway [NCIt concept]
- Primary Immunodeficiency Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cytokine Signaling [NCIt concept]
- Cytokine Signaling Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
- Signal Transduction [NCIt concept]
- V(D)J Recombination [NCIt concept]
is_target
- Fc Fusion IL-7 Mimetic MDK-703 [NCIt concept]
- Ribocytokine IL-7 BNT152 [NCIt concept]

Keyword's position in hierarchy(ies) :

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