Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B

Preferred Label : Low Affinity Immunoglobulin Gamma Fc Region Receptor III-B;

NCIt synonyms : FCGR3B; CD16; FCRIII-1; Fc-Gamma RIIIB; FcRIII; CD16B; Fc Receptor III-1; FcRIIIB; FCGR3; FCG3; Low Affinity IgG Fc Receptor IIIB; Fc-Gamma RIII-Beta; Fc-Gamma RIII; FcR-10; CD16B Antigen; Immunoglobulin G Fc Receptor III-1; IgG Fc Receptor IIIB; IgG Fc Receptor III-1; Neutrophil-Specific Antigen NA; IgG-Fc-Receptor-IIIB;

NCIt definition : Low affinity immunoglobulin gamma Fc region receptor III-B (233 aa, 26 kDa) is encoded by the human FCGR3B gene. This protein plays a role in binding to monomeric or aggregated immunoglobulins.;

NCIt note : Low affinity immunoglobulin gamma Fc region receptor III-B is a GPI-anchored protein and does not appear to mediate either phagocytosis of antigen-antibody complexes or antibody-dependent cytotoxicity.;

Details

Origin ID

C38561;

UMLS CUI

C0966831;

OMIM relation
- Fc fragment of igg receptor iiib [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- CD16b [LOINC component]
- FCGR3B protein, human [MeSH Supplementary Concept]
- FCGR3B protein, human [MeSH concept]
- Lymphocyte antigen CD16b (substance) [SNOMED CT concept]
- lymphocyte antigen cd16b [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- FCGR3B Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Receptor Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Cell Surface Receptor [NCIt concept]
- Fc-Gamma Receptor III [NCIt concept]
gene_product_has_structural_domain_or_motif
- Immunoglobulin-Like C2-Type Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fc Gamma Receptor-Mediated Phagocytosis Pathway [NCIt concept]
- Leishmaniasis Infection Pathway [NCIt concept]
- Natural Killer Cell-Mediated Cytotoxicity Pathway [NCIt concept]
- Phagocytosis Pathway [NCIt concept]
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]

Keyword's position in hierarchy(ies) :

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