Bone Morphogenetic Protein Receptor Type-2

Preferred Label : Bone Morphogenetic Protein Receptor Type-2;

NCIt synonyms : Bone Morphogenetic Protein Receptor, Type II (Serine/Threonine Kinase); BMPR2; BMPR-2; Bone Morphogenetic Protein Receptor Type II; BMP Type II Receptor; EC 2.7.11.30; BMP Type-2 Receptor; BMPR-II; Bone Morphogenetic Protein Receptor Type-II; Type II Activin Receptor-Like Kinase; Bone Morphogenetic Protein Receptor, Type II; Type II Receptor For Bone Morphogenetic Protein-4;

NCIt definition : Bone morphogenetic protein receptor type-2 (1038 aa, 115 kDa) is encoded by the human BMPR2 gene. This protein plays a role in signaling and embryonic pattern formation.;

Details

Origin ID

C21369;

UMLS CUI

C1312154;

Currated CISMeF NLP mapping
- bone morphogenetic protein receptors, type II [MeSH concept]
- bone morphogenetic protein receptors, type ii [MeSH Descriptor]
OMIM relation
- Bone morphogenetic protein receptor, type II [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
- Receptor [UMLS semantic type]
UMLS correspondences (same concept)
- BMPR2 protein, human [MeSH concept]
- BMPR2 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- BMPR2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Phosphotransferase Gene [NCIt concept]
- Receptor Gene [NCIt concept]
- Receptor Serine/Threonine Kinase Gene [NCIt concept]
- Serine/Threonine Protein Kinase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Kinase [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Cytoplasmic Domain [NCIt concept]
- Extracellular Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- ALK Pathway [NCIt concept]
- BMP Receptor Signaling Pathway [NCIt concept]
- Cytokine-Cytokine Receptor Signaling Pathway [NCIt concept]
- TGF-beta Signaling Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Embryogenesis [NCIt concept]
- Ligand Binding [NCIt concept]
- Phosphorylation Process [NCIt concept]
- Protein Phosphorylation Process [NCIt concept]
- Receptor Signaling [NCIt concept]
- Serine/Threonine Phosphorylation [NCIt concept]
- Signal Transduction [NCIt concept]
- Skeletal Development [NCIt concept]

Keyword's position in hierarchy(ies) :

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