" /> Steroidogenic Factor 1 - CISMeF





Preferred Label : Steroidogenic Factor 1;

NCIt synonyms : STF-1; Steroid Hormone Receptor Ad4BP; Fushi Tarazu Factor Homolog 1; Adrenal 4-Binding Protein; Nuclear Receptor Subfamily 5 Group A Member 1; SF-1; NR5A1; Adrenal 4 Binding Protein; Steroidogenic Factor-1; Ad4-Binding Protein; Ad4BP;

NCIt definition : Steroidogenic factor 1 (461 aa, 52 kDa) is encoded by the human NR5A1 gene. This protein plays a role in the activation of transcription of steroidogenic genes.;

NCIt note : Steroidogenic factor 1 binds to the Ad4 site found in the promoter region of steroidogenic P450 genes such as CYP11A, CYP11B and CYP21B. It also binds to the consensus sequences 5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' in a number of gene promoter regions, including those regulating the expression of the AMH, NR0B1 and STAR genes. (UniProt);

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30/07/2025


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