NCIt definition : Steroidogenic factor 1 (461 aa, 52 kDa) is encoded by the human NR5A1 gene. This
protein plays a role in the activation of transcription of steroidogenic genes.;
NCIt note : Steroidogenic factor 1 binds to the Ad4 site found in the promoter region of steroidogenic
P450 genes such as CYP11A, CYP11B and CYP21B. It also binds to the consensus sequences
5'-YCAAGGYC-3' and 5'-RRAGGTCA-3' in a number of gene promoter regions, including
those regulating the expression of the AMH, NR0B1 and STAR genes. (UniProt);