Calcium Homeostasis Modulator Protein 3

Preferred Label : Calcium Homeostasis Modulator Protein 3;

NCIt synonyms : CALHM3; Protein FAM26A;

NCIt definition : Calcium homeostasis modulator protein 3 (344 aa, 38 kDa) is encoded by the human CALHM3 gene. This protein plays a role in the ion channel dependent release of ATP by cells in the taste buds.;

NCIt note : Calcium homeostasis modulator protein 3 forms a fast-activating voltage-gated ATP-release channel with calcium homeostasis modulator protein 1 in type II taste bud cells. (UniProt);

NCI Metathesaurus CUI : CL1926418;

Details

Origin ID

C204123;

UMLS CUI

C5891115;

OMIM relation
- Calcium homeostasis modulator 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Receptor [UMLS semantic type]
gene_encodes_gene_product
- CALHM3 Gene [NCIt concept]
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Circumvallate Papilla [NCIt concept]
gene_product_has_associated_anatomy
- Calcium Channel [NCIt concept]
- Cellular Membrane [NCIt concept]
- Gated Ion Channel [NCIt concept]
- Ion Channel [NCIt concept]
- Plasma Membrane [NCIt concept]
- Type II Epithelial Receptor Cell [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Taste Transduction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Calcium Homeostasis [NCIt concept]
- G Protein-Coupled Receptor Signaling [NCIt concept]
- Gustation [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Neuronal Transmission [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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