Complement Component C1q Receptor

Preferred Label : Complement Component C1q Receptor;

NCIt synonyms : C1qR(p); CD93; C1qRp; Antigen CD93; C1qR; CDw93; Matrix-Remodeling-Associated Protein 4; Complement Component 1 q Subcomponent Receptor 1; C1q/MBL/SPA Receptor; CD93 Antigen; CD93 Molecule;

NCIt definition : Complement component C1q receptor (652 aa, 69 kDa) is encoded by the human CD93 gene. This protein is involved in the clearance of apoptotic cells and intercellular adhesion; it may also bind to complement C1q, mannose-binding lectin and pulmonary surfactant protein A.;

NCIt note : Complement component C1q receptor binding to complement C1q has only been replicated under nonphysiologic conditions; therefore, C1q binding may not be biologically relevant. (EntrezGene, OMIM and UniProt);

NCI Metathesaurus CUI : CL1926443;

Details

Origin ID

C203769;

UMLS CUI

C5890831;

OMIM relation
- Complement component 1, q subcomponent, receptor 1 [OMIM gene]
See also inter- (CISMeF)
- Complement component 1, q subcomponent, receptor 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CD93 Gene [NCIt concept]
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Myeloid Cell [NCIt concept]
- Plasma Membrane [NCIt concept]
- Secretory Vesicle [NCIt concept]
gene_product_has_biochemical_function
- Lectin [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- EGF-Like Domain [NCIt concept]
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cell-Cell Adhesion Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Receptor Signaling [NCIt concept]
is_target
- Anti-CD93 Monoclonal Antibody DCBY02 [NCIt concept]
- Anti-CD93 Monoclonal Antibody DCSZ11 [NCIt concept]

Keyword's position in hierarchy(ies) :

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