NCIt definition : Soluble epidermal growth factor receptor is encoded by the human EGFR gene. This protein
may be involved in the regulation of epidermal growth factor receptor signaling. There
are 3 described isoforms; all soluble forms lack the transmembrane and intracellular
domain of the epidermal growth factor receptor.;
NCIt note : A secreted form of erbB1 that may have utility as a tumor marker.; Soluble epidermal growth factor receptor does not have tyrosine kinase activity.;