Integrin Alpha-IIb

Preferred Label : Integrin Alpha-IIb;

NCIt synonyms : GPIIb; Platelet Membrane Glycoprotein IIb; CD41 Antigen; GPalpha II; GP IIb; Platelet Glycoprotein IIb; ITGA2B;

NCIt definition : Integrin alpha-IIb (1039 aa, 113 kDa) is encoded by the human ITGA2B gene. This protein is involved in the mediation of platelet clotting.;

NCIt note : Integrin alpha-IIb can be cleaved into three products; integrin alpha-IIb heavy chain, integrin alpha-IIb light chain, form 1, integrin alpha-IIb light chain, form 2. (UniProt);

Details

Origin ID

C77160;

UMLS CUI

C0061671;

Currated CISMeF NLP mapping
- platelet membrane glycoprotein IIb [MeSH Descriptor]
- platelet membrane glycoprotein IIb [MeSH concept]
OMIM relation
- Integrin, alpha-2b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- ITGA2B protein, human [MeSH concept]
- ITGA2B protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- ITGA2B Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Integrin Alpha-IIb/Beta-3 [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- Arf6 Signaling Pathway [NCIt concept]
- Arrhythmogenic Right Ventricular Cardiomyopathy Pathway [NCIt concept]
- Dilated Cardiomyopathy Pathway [NCIt concept]
- ECM-Receptor Interaction Signaling Pathway [NCIt concept]
- Ephrin B Reverse Signaling Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hematopoietic Cell Lineage Pathway [NCIt concept]
- Hypertrophic Cardiomyopathy Pathway [NCIt concept]
- IL7 Signaling Pathway [NCIt concept]
- PTPN1 Signaling Pathway [NCIt concept]
- Small Cell Lung Cancer Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Coagulation Process [NCIt concept]
- Heterodimerization [NCIt concept]
- Ligand Binding [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
- Receptor Signaling [NCIt concept]
- Wound Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

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