Metallothionein-3

Preferred Label : Metallothionein-3;

NCIt synonyms : Growth Inhibitory Factor, Brain; GIFB; MT-III; Metallothionein-III; Growth Inhibitory Factor; GIF; Metallothionein III; Growth Inhibitory Factor, Neurotrophic; MT3; Metallothionein 3;

NCIt definition : Metallothionein-3 (68 aa, 7 kDa) is encoded by the human MT3 gene. This protein plays a role in metal binding.;

NCIt note : Metallothionein-3 binds to zinc and copper with high affinitiy. It has a low affinity for cadmium.;

Details

Origin ID

C30075;

UMLS CUI

C0211547;

Automatic exact mappings (from CISMeF team)
- Cobalamin-binding intrinsic factor [OMIM gene]
- GIF [EDAM format]
- Growth Inhibitory Factor [MeSH concept]
- MTI-II [MeSH concept]
- Metallothionein 3 [OMIM gene]
- macrophage migration inhibitory factor [ORDO Gene]
- metallothionein 3 [HGNC gene]
- parathymosin alpha [MeSH Supplementary Concept]
OMIM relation
- Metallothionein 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- human GIF [MeSH concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- MT3 Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
gene_product_malfunction_associated_with_disease
- Alzheimer's Disease [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Nerve Cell Survival [NCIt concept]

Keyword's position in hierarchy(ies) :

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