F1.2 - CISMeF

Preferred Label : F1.2;

NCIt synonyms : F1-2; F1 2; Prothrombin Activation Fragment; Prothrombin Activation Fragment F1.2; Prothrombin Activation Fragment F1-2; Pro-Thrombin Activation Fragment;

NCIt definition : The two peptides that can be released by proteolytic activation of prothrombin to thrombin. The level of these fragments is directly proportional to the amount of active thrombin in a blood sample.;

Details

Origin ID

C105984;

UMLS CUI

C0072436;

Automatic exact mappings (from CISMeF team)
- coagulation factor XII [ORDO Gene]
- prothrombin fragment 1.2 [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- Prothrombin Fragment 1.2 [LOINC component]
- Prothrombin fragment 1.2 (substance) [SNOMED CT concept]
- prothrombin fragment 1.2 [SNOMED Notion]
- prothrombin fragment 1.2 [MeSH Supplementary Concept]
- prothrombin fragment 1.2 [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Coagulation Factor Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- F2 Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_chemical_classification
- Protein Fragment [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Coagulation Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Ligand Binding [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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