P-Selectin Glycoprotein Ligand 1

Preferred Label : P-Selectin Glycoprotein Ligand 1;

NCIt synonyms : CD162; PSGL-1; Cutaneous Lymphocyte Antigen; CLA; CD162 Antigen; Selectin P Ligand; Cutaneous Lymphocyte-Associated Associated Antigen; P-Selectin Glycoprotein Ligand;

NCIt definition : P-selectin glycoprotein ligand 1 (412 aa, 43 kDa) is encoded by the human SELPLG gene. This protein is involved in the modulation of rolling and cell adhesion in circulating leukocytes.;

NCIt note : P-selectin glycoprotein ligand 1 acts as a viral receptor for enterovirus 71. (UniProt);

Details

Origin ID

C128478;

UMLS CUI

C1667075;

Automatic exact mappings (from CISMeF team)
- 6-sulfo sialyl Lewis X [MeSH Supplementary Concept]
- P-selectin ligand protein [MeSH Supplementary Concept]
- Selectin p ligand [OMIM gene]
- linoleic acids, conjugated [MeSH Descriptor]
- lung compliance [MeSH Descriptor]
- selectin P ligand [HGNC gene]
OMIM relation
- Selectin p ligand [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
UMLS correspondences (same concept)
- SELPLG protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Cell Adhesion Molecule Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- SELP Gene [NCIt concept]
gene_product_has_associated_anatomy
- Lymphocyte [NCIt concept]
- Monocyte [NCIt concept]
- Neutrophil [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Viral Receptor [NCIt concept]
gene_product_has_chemical_classification
- Glycoprotein [NCIt concept]
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_biomarker_type
- Cluster of Differentiation [NCIt concept]
gene_product_is_element_in_pathway
- Cell Adhesion Molecule Signaling Pathway [NCIt concept]
- Granulocyte Adhesion Pathway [NCIt concept]
- Local Acute Inflammatory Response Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Adhesion Process [NCIt concept]
- Cellular Migration Process [NCIt concept]
- Interleukin Signaling Process [NCIt concept]
- Ligand Binding [NCIt concept]
is_target
- Neihulizumab [NCIt concept]

Keyword's position in hierarchy(ies) :

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