Sodium-Dependent Dopamine Transporter

Preferred Label : Sodium-Dependent Dopamine Transporter;

NCIt synonyms : DA Transporter; Dopamine Transporter 1; DAT; SLC6A3; Solute Carrier Family 6 Member 3; Dopamine Transporter;

NCIt definition : Sodium-dependent dopamine transporter (620 aa, 68 kDa) is encoded by the human SLC6A3 gene. This protein plays a role in the downregulation of dopamine signaling.;

Details

Origin ID

C113530;

UMLS CUI

C1439340;

Automatic exact mappings (from CISMeF team)
- Alzheimer disease [Radlex concept]
- Magnetic tapes [UNESCO concept]
- Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 [OMIM gene]
- dat [EDAM format]
- dopamine plasma membrane transport proteins [MeSH Descriptor]
- dopamine transport [GO term]
- solute carrier family 6 member 3 [ORDO Gene]
- solute carrier family 6 member 3 [HGNC gene]
OMIM relation
- Solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SLC6A3 protein, human [MeSH Supplementary Concept]
- SLC6A3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Ligand Binding Protein Gene [NCIt concept]
- SLC6A3 Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_biochemical_function
- Solute Carrier Family [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Alpha-Synuclein Signaling Pathway [NCIt concept]
- Parkinson's Disease Pathway KEGG [NCIt concept]
gene_product_plays_role_in_biological_process
- Ligand Binding [NCIt concept]
- Neurotransmitter Activity Inhibition [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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