Preferred Label : Alzheimer disease;
RADLEX synonyms : DAT; dementia Alzheimer type;
Definition : A degenerative disease of the brain characterized by the insidious onset of dementia.
Impairment of memory, judgment, attention span, and problem solving skills are followed
by severe apraxias and a global loss of cognitive abilities. The condition primarily
occurs after age 60, and is marked pathologically by severe cortical atrophy and the
triad of senile plaques; neurofibrillary tangles; and neuropil threads. (From Adams
et al., Principles of Neurology, 6th ed, pp1049-57) [MeSH];
UMLS CUI (RADLEX) : C0002395;
Origin ID : RID5137;
UMLS CUI : C0002395;
Automatic exact mappings (from CISMeF team)
Semantic type(s)
UMLS correspondences (same concept)
Validated automatic mappings to BTNT
A degenerative disease of the brain characterized by the insidious onset of dementia.
Impairment of memory, judgment, attention span, and problem solving skills are followed
by severe apraxias and a global loss of cognitive abilities. The condition primarily
occurs after age 60, and is marked pathologically by severe cortical atrophy and the
triad of senile plaques; neurofibrillary tangles; and neuropil threads. (From Adams
et al., Principles of Neurology, 6th ed, pp1049-57) [MeSH]