Sodium Channel Protein Type 5 Subunit Alpha

Preferred Label : Sodium Channel Protein Type 5 Subunit Alpha;

NCIt synonyms : Cardiac Tetrodotoxin-Insensitive Voltage-Dependent Sodium Channel Alpha Subunit; HH1; Sodium Channel Protein Type V Subunit Alpha; Sodium Channel Protein Cardiac Muscle Subunit Alpha; Voltage-Gated Sodium Channel Subunit Alpha Nav1.5; Voltage-Gated Sodium Channel Alpha Subunit Nav1.5; SCN5A;

NCIt definition : Sodium channel protein type 5 subunit alpha (2016 aa, 227 kDa) is encoded by the human SCN5A gene. This protein is involved in voltage-gated transport of sodium ions.;

Details

Origin ID

C131568;

UMLS CUI

C1143897;

Automatic exact mappings (from CISMeF team)
- Hypogonadotropic hypogonadism 1 with or without anosmia [OMIM Phenotype]
- NAV1.5 Voltage-Gated sodium channel [MeSH Descriptor]
- sodium voltage-gated channel alpha subunit 5 [ORDO Gene]
OMIM relation
- Sodium voltage-gated channel, alpha subunit 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- SCN5A protein, human [MeSH Supplementary Concept]
- SCN5A protein, human [MeSH concept]
gene_encodes_gene_product
- Ion Channel Protein Gene [NCIt concept]
- Ligand Binding Protein Gene [NCIt concept]
- SCN5A Gene [NCIt concept]
- Transport Protein Gene [NCIt concept]
gene_product_expressed_in_tissue
- Intestinal Smooth Muscle Tissue [NCIt concept]
- Myocardium [NCIt concept]
gene_product_has_associated_anatomy
- Cellular Membrane [NCIt concept]
- Ion Channel [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ligand Binding Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Cardiac Muscle Contraction [NCIt concept]
- Ion Transport Process [NCIt concept]
- Ligand Binding [NCIt concept]
- Transmembrane Transport [NCIt concept]
- Transport Process [NCIt concept]
- Voltage-Gated Sodium Ion Channel Activation [NCIt concept]

Keyword's position in hierarchy(ies) :

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